לוח משרות דרושים רפואה ופארמה

innovations for structural heart disease. As part of our R&D Engineering team, you will work closely with our Quality and Manufacturing teams to develop the latest tools and technologies to address significant, unmet clinical needs that impact patients lives around the world.

How you will make an impact :

Design, execute, and support ex-vivo experiments, analyze data, document findings, and clearly communicate results.
Perform hands-on laboratory work, including interventional cardiology procedures in ex-vivo and in-vivo (animal trials) settings, utilizing all available imaging modalities (x-ray, ultrasound, CT).
Collaborate with software engineers and algorithm developers to provide clinical feedback on the implementation of signal processing programs.

A leading biotech company, located in Rehovot, that uses Machine Learning and AI technologies to create superior drugs for cancer and autoimmune disorders by programming antibodies to become dynamic functional switches that affect biology in new ways.
We are seeking a motivated Ph.D. Scientist to join one of our leading programs as a key player in the Drug Discovery department and contribute to the discovery of a novel therapeutic.
As a R&D Scientist, you will significantly contribute to the establishment and implementation of in-vitro antibody characterization essays using cell-based assays and deeper immunological experiments. Key responsibilities:
* A core member of a discovery project team
* Designing and execution of various biological research experiments: cancer cell lines, T and NK cells-based assays
* Developing flow cytometry, immunophenotyping, and other immunological assays
* Analyzing data, documentation, and presentation of scientific and experimental work.
* Identify, suggest, and design mechanisms of action studies (in vitro & in vivo).
* Meeting project goals and timelines.

We are looking for an experienced Clinical MD to manage and oversee our clinical development plan and the medical aspects of advanced-stage clinical trials. In this role, the Clinical MD will address medical inquiries throughout the trial process, contribute to protocol development, and participate in ongoing trial monitoring, including preparing Clinical Study Reports (CSR).

Additionally, the Clinical MD will work closely with internal and external stakeholders to shape the clinical strategy, helping to define the optimal trial path and medical indications required for FDA approval.

Key Responsibilities
Provide medical consultation and support throughout advanced clinical trials, demonstrating a deep understanding of the clinical research process.
Contribute to developing clinical trial protocols, ensuring scientific accuracy and full regulatory compliance.
Oversee the execution of clinical studies, including process monitoring and preparation of Clinical Study Reports (CSRs) summarizing key findings.
Participate in defining the optimal types of trials and clinical indications to support a strong case for FDA approval.
Manage and support the execution of complex clinical programs, including multiple concurrent trials designed to generate comprehensive and robust data.
Supervise small-scale pharmacological studies focusing on pharmacokinetic (PK) and pharmacodynamic (PD) parameters.
Lead preparations for regulatory meetings (e.g., IND), including analysis and interpretation of preclinical pharmacology and PK/PD data.
Define clinical trial objectives and endpoints as part of the overall strategy, ensuring alignment with both medical standards and regulatory expectations.

We are seeking a Clinical Operation Manager to oversee and manage the execution of clinical trials, ensuring compliance with regulatory requirements and alignment with company objectives. This role is pivotal in coordinating clinical operations, supporting global clinical trial execution, vendor management, and data integrity to facilitate successful regulatory submissions.

The Clinical Operation Manager will work closely with internal teams, CROs, regulatory bodies, and external partners to ensure that all clinical trials are conducted efficiently and in compliance with FDA and international regulations.

Key Responsibilities
In collaboration with Head of clinical operations and/or Medical Director,
responsible for comprehensive study management
Lead core team meetings for assigned studies, ensuring goals and deliverables are defined, and issues, decisions, risks, and actions are appropriately tracked
Responsible for managing project-specific vendors, including Study Committees, CRO/ARO, Core Labs, and DSMBs/CECs.
Oversee and support the development of key study documents including, but not limited t,o study protocols and related amendments, study plans and procedure manuals, project tools, training materials, Informed Consent Forms, and Clinical Study Reports.
Accountable for the conduct of clinical study following the approved project plans, budgets, SOPs, and applicable regulations
Support analysis and development of action plans for investigational sites, vendor management, non-compliance, and administrative issues